Discovery of N-(4-(2-Amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (BMS-777607), a Selective and Orally Efficacious Inhibitor of the Met Kinase SuperfamilySCHROEDER, Gretchen M; YONGMI AN; HUNT, John T et al.Journal of medicinal chemistry (Print). 2009, Vol 52, Num 5, pp 1251-1254, issn 0022-2623, 4 p.Article

Identification of 2-amino-5-(thioaryl)thiazoles as inhibitors of nerve growth factor receptor TrkAKIM, Soong-Hoon; TOKARSKI, John S; LIPPY, Jonathan S et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 2, pp 634-639, issn 0960-894X, 6 p.Article

The structure of dasatinib (BMS-354825) bound to activated ABL kinase domain elucidates its inhibitory activity against imatinib-resistant ABL mutantsTOKARSKI, John S; NEWITT, John A; DIANLIN XIE et al.Cancer research (Baltimore). 2006, Vol 66, Num 11, pp 5790-5797, issn 0008-5472, 8 p.Article

Design, Synthesis, and Anti-inflammatory Properties of Orally Active 4-(Phenylamino)-pyrrolo[2,1-/][1,2,4]triazine p38α Mitogen-Activated Protein Kinase InhibitorsHYNES, John; DYCKMAN, Alaric J; PITT, Sidney et al.Journal of medicinal chemistry (Print). 2008, Vol 51, Num 1, pp 4-16, issn 0022-2623, 13 p.Article

New C-5 substituted pyrrolotriazine dual inhibitors of EGFR and HER2 protein tyrosine kinasesMASTALERZ, Harold; CHANGE, Ming; LEE, Francis Y et al.Bioorganic & medicinal chemistry letters (Print). 2007, Vol 17, Num 7, pp 2036-2042, issn 0960-894X, 7 p.Article

Novel C-5 aminomethyl pyrrolotriazine dual inhibitors of EGFR and HER2 protein tyrosine kinasesMASTALERZ, Harold; MING CHANG; TOKARSKI, John S et al.Bioorganic & medicinal chemistry letters (Print). 2007, Vol 17, Num 10, pp 2828-2833, issn 0960-894X, 6 p.Article

Discovery and evaluation of N-cyclopropyl-2,4-difluoro-5-(2-(pyridin-2-ylamino)thiazol-5-ylmethyl)aminobenzamide (BMS-605541), a selective and orally efficacious inhibitor of vascular endothelial growth factor receptor-2BORZILLERI, Robert M; BHIDE, Rajeev S; MARATHE, Punit et al.Journal of medicinal chemistry (Print). 2006, Vol 49, Num 13, pp 3766-3769, issn 0022-2623, 4 p.Article

Discovery of tyrosine-based potent and selective melanocortin-1 receptor small-molecule agonists with anti-inflammatory propertiesHERPIN, Timothy F; GUIXUE YU; MACOR, John E et al.Journal of medicinal chemistry (Print). 2003, Vol 46, Num 7, pp 1123-1126, issn 0022-2623, 4 p.Article

Pyrrolo[1,2-f]triazines as JAK2 inhibitors: Achieving potency and selectivity for JAK2 over JAK3HARIKRISHNAN, Lalgudi S; KAMAU, Muthoni G; POSS, Michael A et al.Bioorganic & medicinal chemistry letters (Print). 2011, Vol 21, Num 5, pp 1425-1428, issn 0960-894X, 4 p.Article

Design, synthesis and structure-activity relationships of novel biarylamine-based Met kinase inhibitorsWILLIAMS, David K; CHEN, Xiao-Tao; HENLEY, Benjamin J et al.Bioorganic & medicinal chemistry letters (Print). 2010, Vol 20, Num 9, pp 2998-3002, issn 0960-894X, 5 p.Article

Discovery of Pyrrolopyridine-Pyridone Based Inhibitors of Met Kinase : Synthesis, X-ray Crystallographic Analysis, and Biological ActivitiesKYOUNG SOON KIM; LIPING ZHANG; YONGMI AN et al.Journal of medicinal chemistry (Print). 2008, Vol 51, Num 17, pp 5330-5341, issn 0022-2623, 12 p.Article

Identification of a novel series of tetrahydrodibenzazocines as inhibitors of 17β-hydroxysteroid dehydrogenase type 3FINK, Brian E; GAVAI, Ashvinikumar V; DAN YOU et al.Bioorganic & medicinal chemistry letters (Print). 2006, Vol 16, Num 6, pp 1532-1536, issn 0960-894X, 5 p.Article

The synthesis and evaluation of [2.2.1]-bicycloazahydantoins as androgen receptor antagonistsBALOG, Aaron; SALVATI, Mark E; KRYSTEK, Stanley R et al.Bioorganic & medicinal chemistry letters (Print). 2004, Vol 14, Num 24, pp 6107-6111, issn 0960-894X, 5 p.Article

Rational design and synthesis of an orally active indolopyridone as a novel conformationally constrained cannabinoid ligand possessing antiinflammatory propertiesWROBLESKI, Stephen T; PING CHEN; GILLOOLY, Kathleen M et al.Journal of medicinal chemistry (Print). 2003, Vol 46, Num 11, pp 2110-2116, issn 0022-2623, 7 p.Article

Discovery and Preclinical Evaluation of [4-[[1-(3-fluorophenyl)methyl]-1H-indazol-5-ylamino]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]carbamic Acid, (3S)-3-Morpholinylmethyl Ester (BMS-599626), a Selective and Orally Efficacious Inhibitor of Human Epidermal Growth Factor Receptor 1 and 2 KinasesGAVAI, Ashvinikumar V; FINK, Brian E; NORRIS, Derek et al.Journal of medicinal chemistry (Print). 2009, Vol 52, Num 21, pp 6527-6530, issn 0022-2623, 4 p.Article

Discovery of orally active pyrrolopyridine-and aminopyridine-based Met kinase inhibitorsCAI, Zhen-Wei; WEI, Donna; SACK, John S et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 11, pp 3224-3229, issn 0960-894X, 6 p.Article

Identification of pyrrolo[2,1-f][1,2,4]triazine-based inhibitors of Met kinaseSCHROEDER, Gretchen M; CHEN, Xiao-Tao; HUYNH, Tram et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 6, pp 1945-1951, issn 0960-894X, 7 p.Article

Design, synthesis, and evaluation of orally active 4-(2,4-difluoro-5-(methoxycarbamoyl)phenylamino)pyrrolo[2,1-f][1,2,4]triazines as dual vascular endothelial growth factor receptor-2 and fibroblast growth factor receptor-1 inhibitorsBORZILLERI, Robert M; XIAOPING ZHENG; KAMATH, Amrita et al.Journal of medicinal chemistry (Print). 2005, Vol 48, Num 12, pp 3991-4008, issn 0022-2623, 18 p.Article

New dual inhibitors of EGFR and HER2 protein tyrosine kinasesFINK, Brian E; VITE, Gregory D; HUNT, John T et al.Bioorganic & medicinal chemistry letters (Print). 2005, Vol 15, Num 21, pp 4774-4779, issn 0960-894X, 6 p.Article

Synthesis and biological activity of N-aryl-2-aminothiazoles: potent pan inhibitors of cyclin-dependent kinasesMISRA, Raj N; XIAO, Hai-Yun; KIMBALL, S. David et al.Bioorganic & medicinal chemistry letters (Print). 2004, Vol 14, Num 11, pp 2973-2977, issn 0960-894X, 5 p.Article